Target

Browse compounds by primary biological target.

For Research Use Only. Not for human or veterinary use.

87 target group(s) / 104 product(s)

Not identified

9 compound(s)

Amidepsine D (CAS: 79786-34-8)

Aspergillin PZ (CAS: 483305-08-4)

Citrinaline A (CAS: 1256635-19-4)

Cycloaspeptide A (CAS: 109171-13-3)

11-O-Methylpseurotin A (CAS: 956904-34-0)

Neoxaline (CAS: 71812-10-7)

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Ferric iron (Fe3+)

4 compound(s)

Dimerumic acid (CAS: 26912-16-3)

Nocardamine (CAS: 26605-16-3)

PF1140 (CAS: 173560-58-2)

Pyridoxatin (CAS: 135529-30-5)

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Protein tyrosine phosphatase 1B (PTP1B)

3 compound(s)

Palitantin (CAS: 15265-28-8)

Penstyrylpyrone (CAS: 1447970-41-3)

Sydowinin B (MS-347b) (CAS: 58450-00-3)

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Acyl-CoA:cholesterol acyltransferase (ACAT)

2 compound(s)

Penicillide (CAS: 55303-92-9)

Terpendole C (CAS: 156967-65-6)

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Hsp90

2 compound(s)

Monocillin IV (CAS: 75207-14-6)

Radicicol (CAS: 12772-57-5)

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Not identified (NGF signaling enhancement)

2 compound(s)

NG 011 (CAS: 151271-58-8)

NG 012 (CAS: 141731-76-2)

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Redox-active quinone systems

2 compound(s)

OM173-alphaA (CAS: 58286-56-9)

Oosporein (CAS: 475-54-7)

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20S proteasome (? subunits)

1 compound(s)

Lactacystin (CAS: 133343-34-7)

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Acetylcholinesterase (AChE)

1 compound(s)

Territrem B (CAS: 70407-20-4)

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Actin cytoskeleton (actin polymerization machinery)

1 compound(s)

Chaetoglobosine A (CAS: 50335-03-0)

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ADP-ribosylation factor guanine nucleotide exchange factors (ARF-GEFs; e.g., GBF1)

1 compound(s)

Brefeldin A (CAS: 20350-15-6)

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agr quorum sensing system; fsr quorum sensing system; Autoinducing peptide (AIP) biosynthesis machinery

1 compound(s)

Ambuic Acid (CAS: 340774-69-8)

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ATP-generating nucleotide biosynthesis enzymes

1 compound(s)

Virustomycin A (CAS: 84777-85-5)

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Autophagy regulatory machinery

1 compound(s)

Asperphenamate (CAS: 63631-36-7)

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Bacterial cytoplasmic membrane

1 compound(s)

Enterocin (CAS: 59678-46-5)

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Bacterial ribosome (tetracycline-sensitive site)

1 compound(s)

Viridicatumtoxin A (CAS: 39277-41-3)

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Bcl-2

1 compound(s)

Aranorosin (CAS: 117184-53-9)

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Cannabinoid CB1 receptor; GPR18

1 compound(s)

Amauromine (CAS: 88360-87-6)

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CCR5; SarA; AgrA

1 compound(s)

Fuscin (CAS: 83-85-2)

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Cell-cycle regulatory machinery

1 compound(s)

Globosuxanthone A (CAS: 917091-74-8)

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Cell-cycle regulatory proteins

1 compound(s)

(-)-Flavomannin A (CAS: 19953-89-0)

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Cellular antioxidant response regulators

1 compound(s)

Citrinin (CAS: 518-75-2)

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Cellular membrane ion gradients

1 compound(s)

Beauvericin (CAS: 26048-05-5)

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Checkpoint kinase 1 (Chk1); Checkpoint kinase 2 (Chk2)

1 compound(s)

Pycnidione (CAS: 149064-34-6)

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Cytochrome P450 RugG

1 compound(s)

(+)-Skyrin (CAS: 602-06-2)

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Diacylglycerol acyltransferase (DGAT)

1 compound(s)

Amidepsine A (CAS: 169181-28-6)

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Dihydrogeodin oxidase

1 compound(s)

Geodin (CAS: 427-63-4)

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Dihydroxyacid dehydratase

1 compound(s)

Aspterric Acid (CAS: 67309-95-9)

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DNA (covalent adduct formation)

1 compound(s)

Sterigmatocystin (CAS: 10048-13-2)

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Elongation factor Tu (EF-Tu); Type III secretion system components

1 compound(s)

Aurodox (CAS: 12704-90-4)

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Enolase 1 (ENO1); Aldolase A (ALDOA); Fumarate hydratase (FH)

1 compound(s)

Macrosphelide A (CAS: 172923-77-2)

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Eukaryotic 60S ribosomal peptidyl transferase center

1 compound(s)

Harzianum A (CAS: 156250-74-7)

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Eukaryotic ribosome

1 compound(s)

Aspirochlorine (CAS: 59978-04-0)

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GC-rich B-DNA

1 compound(s)

Chartreusin (CAS: 6377-18-0)

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Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)

1 compound(s)

Heptelidic Acid (CAS: 74310-84-2)

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Hepatitis C virus replication complex

1 compound(s)

Circumdatin F (CAS: 232922-23-5)

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Histone deacetylases (HDACs)

1 compound(s)

Dihydrochlamydocin (CAS: 157618-75-2)

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HIV-1 gp160; Lipid II; Histidine kinase FsrC; Histidine kinase VanS

1 compound(s)

Siamycin I (CAS: 164802-68-0)

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HIV-1 integrase; Matrix metalloproteinase-1 (MMP-1)

1 compound(s)

Funalenone (CAS: 259728-61-5)

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HIV-1 reverse transcriptase; Human telomerase

1 compound(s)

beta-Rubromycin (CAS: 27267-70-5)

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HMG-CoA synthase

1 compound(s)

1233B (CAS: 34668-61-6)

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HMG-CoA synthase (HMGCS1; mvaS)

1 compound(s)

(R,R)-Hymeglusin (CAS: 29066-42-0)

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Human neutrophil elastase

1 compound(s)

Elasnin (CAS: 68112-21-0)

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Influenza A virus replication machinery

1 compound(s)

Herquline A (CAS: 71812-08-3)

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KRAS

1 compound(s)

Rasfonin (CAS: 303156-68-5)

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Large-conductance Ca2+-activated potassium channel (BKCa)

1 compound(s)

Paxilline (CAS: 57186-25-1)

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Leucyl-tRNA synthetase (LeuRS)

1 compound(s)

Streptochlorin (CAS: 120191-51-7)

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LOX-1; NF-κB; VEGFR-2

1 compound(s)

epi-Aszonalenin A

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Membrane ion transport systems

1 compound(s)

Martinomycin (CAS: 160791-16-2)

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Mitochondrial apoptosis regulators

1 compound(s)

Bostrycin (CAS: 21879-81-2)

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Mitochondrial electron transport chain complexes

1 compound(s)

Ascochlorin (CAS: 26166-39-2)

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Mitochondrial F0F1-ATP synthase

1 compound(s)

17-Hydroxyventuricidin A (CAS: 113204-43-6)

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Mitochondrial respiratory chain; DNA-dependent RNA polymerase

1 compound(s)

Rugulosin (CAS: 23537-16-8)

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Motilin receptor (MLNR)

1 compound(s)

EM574 [Motilide] (CAS: 110480-13-2)

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Multiple cellular regulatory targets

1 compound(s)

Bikaverin (CAS: 33390-21-5)

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Mycobacterium tuberculosis PknG; Amyloid beta (Aβ42)

1 compound(s)

Sclerotiorin (CAS: 549-23-5)

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Myosin light chain kinase (MLCK)

1 compound(s)

MS-347a (CAS: 144678-18-2)

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NF-κB signaling components

1 compound(s)

Cyclopenol (CAS: 20007-85-6)

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NLRP3 inflammasome complex

1 compound(s)

10,11-Dehydrocurvularin (CAS: 1095588-70-7)

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Not fully defined

1 compound(s)

Hitachimycin (CAS: 77642-19-4)

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Not fully defined (heptelidic acid analogue)

1 compound(s)

Hydroheptelidic acid (CAS: 192818-49-8)

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Not fully defined (intracellular mycobacterial target)

1 compound(s)

Lariatin A

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Not fully defined (nematode neuromuscular target inferred)

1 compound(s)

Aspergillimide (CAS: 195966-93-9)

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Not identified (chromone dimer scaffold)

1 compound(s)

Remisporine B (CAS: 571194-06-4)

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Not identified (melanogenesis pathway modulation)

1 compound(s)

Aspochalasin I (CAS: 670225-69-1)

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Not identified (Mycobacterium-selective activity)

1 compound(s)

Calpinactam (CAS: 1205538-83-5)

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Oxidative phosphorylation complexes (OXPHOS system)

1 compound(s)

Zelkovamycin (CAS: 221197-33-7)

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p38 MAPK; AMPK; mTOR

1 compound(s)

Malformin A1 (CAS: 3022-92-2)

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Parasite membrane ion homeostasis components

1 compound(s)

Boromycin (CAS: 34524-20-4)

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Peptide deformylase (PDF)

1 compound(s)

Actinonin (CAS: 13434-13-4)

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Phosphatidylinositol 3-kinase (PI3K)

1 compound(s)

Viridiol (CAS: 23820-80-6)

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Protein farnesyltransferase (FTase)

1 compound(s)

Andrastin A (CAS: 174232-42-9)

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Protein phosphatase 2A (PP2A); Akt

1 compound(s)

Prodigiosin (CAS: 82-89-3)

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Protein tyrosine phosphatase 1B (PTP1B); Myosin light chain kinase (MLCK); Trypanothione reductase

1 compound(s)

Altenusin (CAS: 31186-12-6)

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Proteostasis and autophagy machinery

1 compound(s)

Malformin C (CAS: 59926-78-2)

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Ras/MAPK pathway serine-threonine kinases

1 compound(s)

Hypothemycin (CAS: 76958-67-3)

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Reactive oxygen species (ROS)

1 compound(s)

Pyranonigrin A (CAS: 773855-65-5)

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RhlR quorum sensing regulator

1 compound(s)

Curvularin (CAS: 10140-70-2)

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SARS-CoV-2 main protease (Mpro); NF-κB signaling components

1 compound(s)

Cyclopenin (CAS: 19553-26-5)

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Sterol O-acyltransferase 2 (SOAT2; ACAT2)

1 compound(s)

Pyripyropene A (CAS: 147444-03-9)

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Succinate dehydrogenase (Complex II)

1 compound(s)

Atpenin A5 (CAS: 119509-24-9)

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Succinate dehydrogenase (Complex II); Zika virus RNA-dependent RNA polymerase

1 compound(s)

Harzianopyridone (CAS: 126637-69-2)

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Tau protein; p38 MAPK; JNK

1 compound(s)

Fulvic Acid (CAS: 479-66-3)

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Trypanosome alternative oxidase (TAO)

1 compound(s)

Ascofuranone (CAS: 38462-04-3)

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Tumor necrosis factor alpha (TNF-α)

1 compound(s)

Quinolactacin A

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Vacuolar-type H+-ATPase (V-ATPase)

1 compound(s)

Concanamycin B (CAS: 81552-33-2)

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α-Glucosidase; Aryl hydrocarbon receptor (AhR)

1 compound(s)

Vermistatin (CAS: 72669-21-7)

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