Name: Circumdatin F
Brand: Biolinks K.K.
SKU: BLK-1520
Price: 360.00 USD
Availability: InStock

For Research Use Only. Not for human or veterinary use.

Circumdatin F (CAS: 232922-23-5) Product ID: BLK-1520 CAS 232922-23-5 Mechanism Antiviral alkaloid Primary Target Hepatitis C virus replication complex Pathway Viral replication pathway
Structure	View full structure page Chemical structure of Circumdatin F (CAS 232922-23-5)
CAS	232922-23-5
Molecular Formula	C17H13N3O2
Molecular Weight	291.13
Price	1mg: USD 360.00 / 5mg: - / 25mg: -
Storage	-20°C
Solubility	1mg/ml ethanol, methanol, DMSO
Purity	>95% [View LC/UV Data]
LC/UV	Representative LC/UV chromatogram under typical analytical conditions (C18 column; mobile phase: 5–100% ACN / H2O (0.05% H3PO4), linear gradient 20 min; flow rate: 0.2 mL/min; detection: 210 nm).
NMR Data	1H NMR (CDCl3, 500 MHz) [View] [Full page] 13C NMR (CDCl3, 125 MHz) [View] [Full page]
NMR Spectral Data	Representative 1H NMR (CDCl3, 500 MHz) spectrum confirming the structure of Circumdatin F. Representative 13C NMR (CDCl3, 125 MHz) spectrum supporting structural assignment of Circumdatin F.
Source Organism	Aspergillus westerdijkiae.
Summary	Circumdatin F is a fungal quinazolinobenzodiazepine alkaloid studied in antiviral research.
Details	Circumdatin F is a quinazolino[3,2-a][1,4]benzodiazepinedione alkaloid isolated from Aspergillus species. It has been reported to inhibit the final stage of hepatitis C virus polyprotein processing and exhibits activity in antifouling models by modulating marine microbial community composition. Structurally, it contains fused quinazolinone and benzodiazepinone moieties typical of fungal benzodiazepine alkaloids. Circumdatin F serves as a useful scaffold for studying antiviral mechanisms and environmentally friendly antifouling strategies.
Browse Related	Mechanism Antiviral alkaloid Open full index Primary Target Hepatitis C virus replication complex Open full index Pathway Viral replication pathway Open full index Chemical Class Quinazolinobenzodiazepine alkaloid Open full index
Mechanism	Antiviral alkaloid
Primary Target	Hepatitis C virus replication complex
Pathway	Viral replication pathway
Chemical Class	Quinazolinobenzodiazepine alkaloid
Discovery Year	2000
Keywords	quinazolinobenzodiazepine alkaloid antiviral compound hcv polyprotein processing inhibitor antifouling agent marine biofilm modulator aspergillus metabolite benzodiazepine scaffold natural product research tool
References	Arai et al., J Nat Prod, 2000 DOI: 10.1021/np000381u Takahashi et al., J Org Chem, 2001 DOI: 10.1021/jo001696h Chen et al., Sci Total Environ, 2021 DOI: 10.1016/j.scitotenv.2021.152910
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Representative LC/UV Data HPLC Conditions (typical): Column: C18 Mobile phase: 5–100% ACN / H2O (0.05% H3PO4), linear gradient 20 min Flow rate: 0.2 mL/min Detection: 210 nm Representative analytical data. Actual batch data may vary.
Representative NMR Data 1H NMR (CDCl3, 500 MHz) Representative spectral data. Actual batch data may vary.
Representative NMR Data 13C NMR (CDCl3, 125 MHz) Representative spectral data. Actual batch data may vary.
Representative NMR Data 1H NMR (CDCl3, 500 MHz) 13C NMR (CDCl3, 125 MHz) Representative spectral data. Actual batch data may vary.

Circumdatin F (CAS: 232922-23-5)