About Biolinks K.K.

Microbial-derived natural compounds for research use.

Biolinks K.K. is a Japan-based manufacturer of microbial-derived natural compounds for research use.

Since 2006, we have specialized in the production of bioactive natural products derived from microorganisms, building a portfolio of approximately 100 compounds supplied worldwide.

All compounds are manufactured in-house, covering the entire process from fermentation to purification and structure determination. This integrated approach ensures consistent quality and traceability at the molecular level.

Our products have been supplied for many years through OEM partnerships with international research reagent companies, supporting both academic and industrial research.

Why Biolinks?

Direct manufacturer with full control over fermentation, purification, and structural analysis
Access to rare and difficult-to-synthesize microbial metabolites
Proven OEM supply to global research reagent companies
Direct communication with the production source
Academic collaboration network with Kitasato University / Institute

All compounds are structurally verified by NMR and high-resolution mass spectrometry (HRMS).

Our analytical capabilities also include LC/UV analysis for purity assessment.

We welcome academic collaborations and joint research opportunities.

Selected compounds include Heptelidic acid, Nocardamine, Hymeglusin, Radicicol, Brefeldin A, Lactacystin, Ascofuranone, Ascochlorin, Aurodox, and Andrastin A.

Facilities

Biolinks maintains in-house infrastructure for microbial fermentation, purification, and structural analysis. Our workflow integrates fermentation systems, downstream processing, LC/UV analysis, LC-MS, NMR analysis, and purification equipment to support the production of research-grade microbial natural products.

Rotary evaporator purification system at Biolinks

Purification & Solvent Removal

Rotary evaporator systems used for concentration and solvent removal during downstream purification of microbial metabolites.

Microbial fermentation process at Biolinks

Fermentation & Downstream Processing

Microbial culture processing and recovery workflow for natural product manufacturing and purification.

LC-MS Analysis

Liquid chromatography and mass spectrometry systems used for analytical characterization and compound verification.

LC/UV Purity Analysis

Agilent LC/UV analytical systems used for purity assessment and chromatographic analysis of microbial metabolites.

NMR Structural Verification

JEOL NMR instrumentation used for structural confirmation and molecular characterization of natural products.

Academic Collaboration

Biolinks maintains research activities in collaboration with academic laboratories at the Ōmura Satoshi Memorial Institute, Kitasato University, supporting microbial natural product research and analytical studies.

Laboratory of Applied Microbial Chemistry, Kitasato University

Contact

For general inquiries, distributor inquiries, or technical questions, please contact us at:

support【at】biolinks.co.jp

Please replace 【at】 with @ when sending your email.

For Research Use Only. Not for human or veterinary use.