Name: Ascochlorin
Brand: Biolinks K.K.
SKU: BLK-1440
Price: 520.00 USD
Availability: InStock

For Research Use Only. Not for human or veterinary use.

Ascochlorin (CAS: 26166-39-2) Product ID: BLK-1440 CAS 26166-39-2 Mechanism Mitochondrial electron transport inhibitor Primary Target Mitochondrial electron transport chain complexes Pathway Oxidative phosphorylation; Wnt/β-catenin signaling pathway
Structure	View full structure page Chemical structure of Ascochlorin (CAS 26166-39-2)
CAS	26166-39-2
Molecular Formula	C23H29ClO4
Molecular Weight	404.94
Price	1mg: USD 520.00 / 5mg: - / 25mg: -
Storage	-20°C
Solubility	1mg/ml ethanol, methanol, DMSO
Synonyms	LL-Z1272?
Purity	>95% [View LC/UV Data]
LC/UV	Representative LC/UV chromatogram under typical analytical conditions (C18 column; mobile phase: 60–100% ACN / H2O (0.05% H3PO4), linear gradient 20 min; flow rate: 0.2 mL/min; detection: 210 nm).
NMR Spectral Data	Representative 1H NMR (500 MHz) spectrum confirming the structure of Ascochlorin. Representative 13C NMR (125 MHz) spectrum supporting structural assignment of Ascochlorin.
Source Organism	Cosmospora sp.
Summary	Ascochlorin is a fungal isoprenoid metabolite that disrupts mitochondrial respiration and is studied in antiviral and anticancer research.
Details	Ascochlorin is an isoprenoid antibiotic originally isolated from Ascochyta viciae. Structurally resembling ubiquinone derivatives, it modulates mitochondrial electron transport and has been reported to interfere with respiratory chain function. Ascochlorin exhibits diverse biological activities, including antiviral effects, induction of apoptosis or caspase-independent necroptosis in immune and tumor cells, and inhibition of adipogenesis via modulation of the Wnt/β-catenin pathway. These multifunctional properties position ascochlorin as a pleiotropic natural product with potential applications in cancer, metabolic disease, and antiviral research.
Browse Related	Mechanism Mitochondrial electron transport inhibitor Open full index Primary Target Mitochondrial electron transport chain complexes Open full index Pathway Oxidative phosphorylation; Wnt/β-catenin signaling pathway Open full index Chemical Class Isoprenoid meroterpenoid Open full index
Mechanism	Mitochondrial electron transport inhibitor
Primary Target	Mitochondrial electron transport chain complexes
Pathway	Oxidative phosphorylation; Wnt/β-catenin signaling pathway
Chemical Class	Isoprenoid meroterpenoid
Discovery Year	1969
Keywords	mitochondrial respiration inhibitor mitochondrial complex iii modulator electron transport chain inhibitor apoptosis inducer wnt β-catenin pathway inhibitor isoprenoid natural product fungal metabolite metabolic research compound
References	Takahashi N et al., Antimicrob Agents Chemother, 1969, 17:825-829 DOI: 10.1128/am.17.6.825-829.1969 Lee JH et al., J Ethnopharmacol, 2019, 239:111898 DOI: 10.1016/j.jep.2019.111898 Kim SJ et al., Int J Mol Sci, 2024, 25:10226 DOI: 10.3390/ijms251810226
Request pricing, availability, or bulk supply information for this compound. Get a Quote General Inquiry
Documents 📄 Safety Data Sheet (SDS) – Download PDF 📄 Product Specification Sheet (PDS) – Download PDF 🧪 Certificate of Manufacture (CofM) – Download HTML
← Back to Catalog
Representative LC/UV Data HPLC Conditions (typical): Column: C18 Mobile phase: 60–100% ACN / H2O (0.05% H3PO4), linear gradient 20 min Flow rate: 0.2 mL/min Detection: 210 nm Representative analytical data. Actual batch data may vary.

Ascochlorin (CAS: 26166-39-2)