Name: Bostrycin
Brand: Biolinks K.K.
SKU: BLK-1370
Price: 200.00 USD
Availability: InStock

For Research Use Only. Not for human or veterinary use.

Bostrycin (CAS: 21879-81-2) Product ID: BLK-1370 CAS 21879-81-2 Mechanism ROS inducer Primary Target Mitochondrial apoptosis regulators Pathway Mitochondrial apoptosis; Oxidative stress response; Central carbon metabolism
Structure	View full structure page Chemical structure of Bostrycin (CAS 21879-81-2)
CAS	21879-81-2
Molecular Formula	C16H16O8
Molecular Weight	336.3
Price	1mg: USD 200.00 / 5mg: - / 25mg: -
Storage	-20°C
Solubility	1mg/ml DMSO
Purity	>95% [View LC/UV Data]
LC/UV	Representative LC/UV chromatogram under typical analytical conditions (C18 column; mobile phase: 5–100% ACN / H2O (0.05% H3PO4), linear gradient 20 min; flow rate: 0.2 mL/min; detection: 210 nm).
NMR Spectral Data	Representative 1H NMR (500 MHz) spectrum confirming the structure of Bostrycin. Representative 13C NMR (125 MHz) spectrum supporting structural assignment of Bostrycin.
Source Organism	Arthrinium sp.
Summary	Bostrycin is an anthraquinone phytotoxin with anticancer and antimycobacterial activity.
Details	Bostrycin is an anthraquinone pigment originally isolated from Alternaria species and identified as a nonspecific phytotoxin capable of inducing necrosis in plant tissues. Beyond its phytotoxic effects, bostrycin exhibits antimicrobial activity and inhibits the growth of Mycobacterium tuberculosis. In cancer models, bostrycin suppresses proliferation and migration of tumor cells by inducing G2/M cell-cycle arrest and triggering mitochondrial apoptosis. Proteomic studies suggest that bostrycin may induce oxidative stress and interfere with NAD+ synthesis and TCA-cycle processes, highlighting its multifunctional biological activity.
Browse Related	Mechanism ROS inducer Open full index Primary Target Mitochondrial apoptosis regulators Open full index Pathway Mitochondrial apoptosis; Oxidative stress response; Central carbon metabolism Open full index Chemical Class Anthraquinone Open full index
Mechanism	ROS inducer
Primary Target	Mitochondrial apoptosis regulators
Pathway	Mitochondrial apoptosis; Oxidative stress response; Central carbon metabolism
Chemical Class	Anthraquinone
Discovery Year	1982
Keywords	anthraquinone phytotoxin mitochondrial apoptosis inducer g2 m cell cycle arrest oxidative stress inducer anticancer research compound alternaria metabolite fungal secondary metabolite
References	Charudattan et al., Appl Environ Microbiol, 1982 DOI: 10.1128/aem.43.4.846-849.1982 Zhang et al., Transl Cancer Res, 2020 DOI: 10.21037/tcr-19-2076 Liu et al., J Proteomics, 2019 DOI: 10.1016/j.jprot.2019.103576
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Representative LC/UV Data HPLC Conditions (typical): Column: C18 Mobile phase: 5–100% ACN / H2O (0.05% H3PO4), linear gradient 20 min Flow rate: 0.2 mL/min Detection: 210 nm Representative analytical data. Actual batch data may vary.

Bostrycin (CAS: 21879-81-2)