Name: Beauvericin
Brand: Biolinks K.K.
SKU: BLK-0370
Price: 32.00 USD
Availability: InStock

For Research Use Only. Not for human or veterinary use.

Beauvericin (CAS: 26048-05-5) Product ID: BLK-0370 CAS 26048-05-5 Mechanism Ionophore Primary Target Cellular membrane ion gradients Pathway Ion homeostasis; Mitochondrial apoptosis
Structure	View full structure page Chemical structure of Beauvericin (CAS 26048-05-5)
CAS	26048-05-5
Molecular Formula	C45H57N3O9
Molecular Weight	783.97
Price	1mg: USD 32.00 / 5mg: - / 25mg: -
Storage	-20°C
Solubility	1mg/ml ethanol, methanol, DMSO
Purity	>95% [View LC/UV Data]
LC/UV	Representative LC/UV chromatogram under typical analytical conditions (C18 column; mobile phase: 5–100% ACN / H2O (0.05% H3PO4), linear gradient 20 min; flow rate: 0.2 mL/min; detection: 210 nm).
NMR Data	1H NMR (CDCl3, 500 MHz) [View] [Full page] 13C NMR (CDCl3, 125 MHz) [View] [Full page]
NMR Spectral Data	Representative 1H NMR (CDCl3, 500 MHz) spectrum confirming the structure of Beauvericin. Representative 13C NMR (CDCl3, 125 MHz) spectrum supporting structural assignment of Beauvericin.
Source Organism	Beauveria sp.
Summary	Beauvericin is a cyclic ionophoric mycotoxin with antimicrobial and anticancer activity.
Details	Beauvericin is a cyclic hexadepsipeptide mycotoxin produced by Fusarium and other filamentous fungi. It acts as a cation-selective ionophore, disrupting ion homeostasis and inducing mitochondrial dysfunction, oxidative stress, and apoptosis. Beauvericin exhibits antimicrobial, antiviral, antifungal, insecticidal, and anticancer activities, while also being recognized as an emerging food and feed contaminant with documented in vitro and in vivo toxicological effects.
Browse Related	Mechanism Ionophore Open full index Primary Target Cellular membrane ion gradients Open full index Pathway Ion homeostasis; Mitochondrial apoptosis Open full index Chemical Class Cyclic hexadepsipeptide (enniatin family) Open full index
Mechanism	Ionophore
Primary Target	Cellular membrane ion gradients
Pathway	Ion homeostasis; Mitochondrial apoptosis
Chemical Class	Cyclic hexadepsipeptide (enniatin family)
Discovery Year	1969
Keywords	cyclic hexadepsipeptide ionophore mitochondrial dysfunction inducer apoptosis inducer reactive oxygen species generator fusarium metabolite enniatin family mycotoxin cytotoxic research compound
References	Mancebo et al., Environ Toxicol Pharmacol, 2020 DOI: 10.1016/j.etap.2020.103349 Prosperini et al., Toxins, 2020 DOI: 10.3390/toxins12110686 Tolosa et al., Toxins, 2021 DOI: 10.3390/toxins13010032
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Documents 📄 Safety Data Sheet (SDS) – Download PDF 📄 Product Specification Sheet (PDS) – Download PDF 🧪 Certificate of Manufacture (CofM) – Download HTML
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Representative LC/UV Data HPLC Conditions (typical): Column: C18 Mobile phase: 5–100% ACN / H2O (0.05% H3PO4), linear gradient 20 min Flow rate: 0.2 mL/min Detection: 210 nm Representative analytical data. Actual batch data may vary.
Representative NMR Data 1H NMR (CDCl3, 500 MHz) Representative spectral data. Actual batch data may vary.
Representative NMR Data 13C NMR (CDCl3, 125 MHz) Representative spectral data. Actual batch data may vary.
Representative NMR Data 1H NMR (CDCl3, 500 MHz) 13C NMR (CDCl3, 125 MHz) Representative spectral data. Actual batch data may vary.

Beauvericin (CAS: 26048-05-5)