Name: Viridiol
Brand: Biolinks K.K.
SKU: BLK-0860
Price: 160.00 USD
Availability: InStock

For Research Use Only. Not for human or veterinary use.

Viridiol (CAS: 23820-80-6) Product ID: BLK-0860 CAS 23820-80-6 Mechanism PI3K inhibitor Primary Target Phosphatidylinositol 3-kinase (PI3K) Pathway PI3K/AKT signaling pathway
Structure	View full structure page Chemical structure of Viridiol (CAS 23820-80-6)
CAS	23820-80-6
Molecular Formula	C20H18O6
Molecular Weight	354.36
Price	1mg: USD 160.00 / 5mg: - / 25mg: -
Storage	-20°C
Solubility	1mg/ml ethanol, methanol, DMSO
Purity	>95% [View LC/UV Data]
LC/UV	Representative LC/UV chromatogram under typical analytical conditions (C18 column; mobile phase: 5–100% ACN / H2O (0.05% H3PO4), linear gradient 20 min; flow rate: 0.2 mL/min; detection: 210 nm).
NMR Spectral Data	Representative 1H NMR (500 MHz) spectrum confirming the structure of Viridiol. Representative 13C NMR (125 MHz) spectrum supporting structural assignment of Viridiol.
Source Organism	Trichoderma sp.
Summary	Viridiol is a furanosteroid derived from viridin that inhibits PI3K.
Details	Viridiol is a furanosteroidal secondary metabolite produced by viridin-producing fungi such as Gliocladium virens (Trichoderma virens). It arises via enzymatic reduction of the antifungal compound viridin and can also be generated through environmental microbial bioconversion. Viridiol has been identified as a potent inhibitor of phosphatidylinositol 3-kinase (PI3K), a key regulator of cellular growth and survival signaling pathways. Production studies demonstrated scalable preparation from T. virens cultures, and synthetic work established enantioselective access to viridiol and related furanosteroids. Due to its phytotoxic properties and PI3K inhibitory activity, viridiol serves as both a bioactive natural product probe and a tool compound for studying PI3K-associated signaling.
Browse Related	Mechanism PI3K inhibitor Open full index Primary Target Phosphatidylinositol 3-kinase (PI3K) Open full index Pathway PI3K/AKT signaling pathway Open full index Chemical Class Furanosteroid meroterpenoid Open full index
Mechanism	PI3K inhibitor
Primary Target	Phosphatidylinositol 3-kinase (PI3K)
Pathway	PI3K/AKT signaling pathway
Chemical Class	Furanosteroid meroterpenoid
Discovery Year	1987
Keywords	furanosteroid natural product phosphatidylinositol 3-kinase (pi3k) inhibitor trichoderma virens metabolite viridin derivative phytotoxic compound fungal secondary metabolite signal transduction research tool
References	Howell et al., Can J Microbiol, 1987 (conversion of viridin to viridiol; phytotoxicity) DOI: 10.1139/m87-169 McDonald et al., J Am Chem Soc, 2017 (enantioselective synthesis of (-)-viridin and (-)-viridiol) DOI: 10.1021/jacs.7b02829 Kong et al., Bioorg Chem, 2021 (bioconversion of viridin to viridiol by environmental microorganisms) DOI: 10.1016/j.bioorg.2021.104959 Tanaka et al., Sci Rep, 2025 (scalable production; PI3K inhibitory furanosteroids from Trichoderma virens) DOI: 10.1038/s41598-025-87070-z
Request pricing, availability, or bulk supply information for this compound. Get a Quote General Inquiry
Documents 📄 Safety Data Sheet (SDS) – Download PDF 📄 Product Specification Sheet (PDS) – Download PDF 🧪 Certificate of Manufacture (CofM) – Download HTML
← Back to Catalog
Representative LC/UV Data HPLC Conditions (typical): Column: C18 Mobile phase: 5–100% ACN / H2O (0.05% H3PO4), linear gradient 20 min Flow rate: 0.2 mL/min Detection: 210 nm Representative analytical data. Actual batch data may vary.

Viridiol (CAS: 23820-80-6)