Representative 1H NMR (500 MHz) spectrum confirming the structure of Remisporine B. Representative 13C NMR (125 MHz) spectrum supporting structural assignment of Remisporine B.
Summary
Remisporine B is a rare fungal chromone-derived dimer with defined absolute configuration.
Details
Remisporine B is a fungal secondary metabolite featuring a rare chromone-derived cyclopentadienyl core formed through a proposed Diels-Alder-type dimerization of remisporine A. Its absolute configuration was determined by comparison of experimental and density functional theory-calculated electronic circular dichroism spectra. Biogenetic analysis supports a rearrangement pathway related to benzyl benzilic acid-type transformations.