Name: Aspergillin PZ
Brand: Biolinks K.K.
SKU: BLK-1220
Price: 110.00 USD
Availability: InStock

For Research Use Only. Not for human or veterinary use.

Aspergillin PZ (CAS: 483305-08-4) Product ID: BLK-1220 CAS 483305-08-4 Mechanism Fungal morphogenesis disruptor Primary Target Not identified Pathway Secondary metabolite biosynthesis
Structure	View full structure page Chemical structure of Aspergillin PZ (CAS 483305-08-4)
CAS	483305-08-4
Molecular Formula	C24H35NO4
Molecular Weight	401.55
Price	1mg: USD 110.00 / 5mg: - / 25mg: -
Storage	-20°C
Solubility	1mg/ml ethanol, methanol, DMSO
Purity	>95% [View LC/UV Data]
LC/UV	Representative LC/UV chromatogram under typical analytical conditions (C18 column; mobile phase: 5–100% ACN / H2O (0.05% H3PO4), linear gradient 20 min; flow rate: 0.2 mL/min; detection: 210 nm).
NMR Spectral Data	Representative 1H NMR (500 MHz) spectrum confirming the structure of Aspergillin PZ. Representative 13C NMR (125 MHz) spectrum supporting structural assignment of Aspergillin PZ.
Source Organism	Aspergillus sp.
Summary	Aspergillin PZ is an isoindole alkaloid from Aspergillus awamori featuring a distinctive oxabicyclic core.
Details	Aspergillin PZ is a fungal isoindole alkaloid isolated from Aspergillus awamori and characterized by a rare oxabicyclic ring system confirmed by X-ray crystallography. It was found to moderately induce morphological deformation of Pyricularia oryzae conidia. The structural complexity of aspergillin PZ has attracted synthetic interest, and its total synthesis was achieved via a 2-oxonia[3,3]sigmatropic rearrangement/aldol cascade mechanism. Although synthetic material showed limited cytotoxic activity, aspergillin PZ remains a notable example of a structurally remarkable fungal alkaloid.
Browse Related	Mechanism Fungal morphogenesis disruptor Open full index Primary Target Not identified Open full index Pathway Secondary metabolite biosynthesis Open full index Chemical Class Isoindole alkaloid Open full index
Mechanism	Fungal morphogenesis disruptor
Primary Target	Not identified
Pathway	Secondary metabolite biosynthesis
Chemical Class	Isoindole alkaloid
Discovery Year	2002
Keywords	isoindole alkaloid oxabicyclic scaffold fungal secondary metabolite aspergillus awamori metabolite conidia morphology modulator heterocyclic alkaloid scaffold
References	Kobayashi M et al., J Antibiot (Tokyo), 2002, 55:693-697 DOI: 10.7164/antibiotics.55.693 Clark JS et al., Tetrahedron, 2011, 67:8927-8936 DOI: 10.1016/j.tet.2011.09.079
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Representative LC/UV Data HPLC Conditions (typical): Column: C18 Mobile phase: 5–100% ACN / H2O (0.05% H3PO4), linear gradient 20 min Flow rate: 0.2 mL/min Detection: 210 nm Representative analytical data. Actual batch data may vary.

Aspergillin PZ (CAS: 483305-08-4)