Name: Amidepsine D
Brand: Biolinks K.K.
SKU: BLK-0314
Price: 210.00 USD
Availability: InStock

For Research Use Only. Not for human or veterinary use.

Amidepsine D (CAS: 79786-34-8) Product ID: BLK-0314 CAS 79786-34-8 Mechanism Uncharacterized mechanism Primary Target Not identified Pathway Secondary metabolite biosynthesis
Structure	View full structure page Chemical structure of Amidepsine D (CAS 79786-34-8)
CAS	79786-34-8
Molecular Formula	C26H24O10
Molecular Weight	496.47
Price	1mg: USD 210.00 / 5mg: - / 25mg: -
Storage	-20°C
Solubility	1mg/ml ethanol, methanol, DMSO
Synonyms	2,4-di-O-methylgryphoric acid
Purity	>95% [View LC/UV Data]
LC/UV	Representative LC/UV chromatogram under typical analytical conditions (C18 column; mobile phase: 30–70% ACN / H2O (0.05% H3PO4), linear gradient 20 min; flow rate: 0.2 mL/min; detection: 210 nm).
NMR Spectral Data	Representative 1H NMR (500 MHz) spectrum confirming the structure of Amidepsine D. Representative 13C NMR (125 MHz) spectrum supporting structural assignment of Amidepsine D.
Source Organism	Humicola sp.
Summary	Amidepsine D is a fungal depside structurally related to DGAT-inhibiting amidepsines and studied as a lipid biosynthesis scaffold.
Details	Amidepsine D is a fungal secondary metabolite isolated from the DGAT inhibitor-producing strain Humicola sp. FO-2942. Structural analysis identified amidepsine D as 2,4-di-O-methylgryphoric acid, a depside-type aromatic compound. Unlike amidepsines A-C, which possess N-alanine or N-valine amide moieties and exhibit DGAT inhibitory activity, amidepsine D corresponds to a methylated gryphoric acid derivative and represents a structurally related metabolite from the same biosynthetic context.
Browse Related	Mechanism Uncharacterized mechanism Open full index Primary Target Not identified Open full index Pathway Secondary metabolite biosynthesis Open full index Chemical Class Depside Open full index
Mechanism	Uncharacterized mechanism
Primary Target	Not identified
Pathway	Secondary metabolite biosynthesis
Chemical Class	Depside
Discovery Year	1995
Keywords	depside natural product gryphoric acid derivative fungal metabolite amidepsine-related compound secondary metabolite scaffold
References	Omura S et al., J Antibiot (Tokyo), 1995, 48:937-941 DOI: 10.7164/antibiotics.48.937 Omura S et al., J Antibiot (Tokyo), 1995, 48:942-945 DOI: 10.7164/antibiotics.48.942
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Representative LC/UV Data HPLC Conditions (typical): Column: C18 Mobile phase: 30–70% ACN / H2O (0.05% H3PO4), linear gradient 20 min Flow rate: 0.2 mL/min Detection: 210 nm Representative analytical data. Actual batch data may vary.

Amidepsine D (CAS: 79786-34-8)