BIOLINKS

For Research Use Only. Not for human or veterinary use.

Aspirochlorine

Product ID: BLK-1600
Structurestructure
CAS59978-04-0
Molecular FormulaC12H9ClN2O5S2
Molecular Weight360.8
UN (Transport)UN 2811
Price1mg: USD 360.00 / 5mg: - / 25mg: -
Storage-20°C
Solubility1mg/ml ethanol, methanol, DMSO
Purity>95%
Source OrganismAspergillus sp.
SummaryAspirochlorine Aspergillus-derived epipolythiodioxopiperazine (ETP) that inhibits fungal protein synthesis and overcomes azole resistance.
Details
MechanismInhibits fungal protein synthesis via ETP-mediated disruption of translation machinery.
Primary TargetEukaryotic ribosome
PathwayFungal protein translation
Chemical ClassEpidithiodiketopiperazine (ETP)
Discovery Year1999
Keywords
epidithiodiketopiperazinefungal protein synthesis inhibitorazole-resistant antifungalcandida albicans inhibitorsulfur-containing diketopiperazinespiroaminal scaffoldfungal secondary metaboliteantifungal research tool
References
  1. Kudo Y et al., J Antibiot (Tokyo), 1999, 52:311-318
    DOI: 10.7164/antibiotics.52.311
  2. Todd JS et al., J Nat Prod, 2006, 69:344-348
    DOI: 10.1021/np050141k
  3. Schneider P et al., J Am Chem Soc, 2020, 142:18987-18996
    DOI: 10.1021/jacs.0c08879
  4. Schneider P et al., Angew Chem Int Ed, 2018, 57:15403-15407
    DOI: 10.1002/anie.201806740
Documents
📄
Safety Data Sheet (SDS) – Download PDF
📄
Product Specification Sheet (PDS) – Download PDF
← Back to Catalog
You may also be interested in
Aspergillin PZ
ProductID: BLK-1220
CAS: 483305-08-4
Aspochalasin I
ProductID: BLK-1270
CAS: 670225-69-1
Asperphenamate
ProductID: BLK-1240
CAS: 63631-36-7
Bostrycin
ProductID: BLK-1370
CAS: 21879-81-2
Bikaverin
ProductID: BLK-1070
CAS: 33390-21-5
Pyridoxatin
ProductID: BLK-1080
CAS: 135529-30-5
© 2026 Biolinks K.K.
Contact | About
Biolinks K.K. (Tokyo, Japan)
Minami-Oi, Shinagawa-ku, Tokyo 140-0013, Japan
For Research Use Only. Not for human or veterinary use.