Talarolutin D – Meroterpenoid with no clearly defined mole...

For Research Use Only. Not for human or veterinary use.

Talarolutin D Product ID: BLK-1530
Structure
CAS	1904635-42-2
Molecular Formula	C21H28O5
Molecular Weight	360.45
Price	1mg: USD 360.00 / 5mg: - / 25mg: -
Storage	-20°C
Solubility	1mg/ml ethanol, methanol, DMSO
Purity	>95%
Source Organism	Talaromyces sp.
Summary	Talarolutin D Meroterpenoid isolated from Talaromyces minioluteus.
Details	Talarolutin D is one of four meroterpenoids (talarolutins A縫) isolated from an endophytic fungal strain of Talaromyces minioluteus obtained from the leaves of Silybum marianum. Its structure was elucidated using NMR and MS analyses, with stereochemical assignments supported by NOESY and ECD comparisons within the talarolutin series. In biological evaluation, talarolutins B縫 were tested for cytotoxicity against human prostate carcinoma (PC-3) cells, antimicrobial activity, and induction of quinone reductase, but no notable activity was observed in these assays. Thus, talarolutin D is currently characterized primarily as a structurally defined fungal meroterpenoid without confirmed bioactivity.
Mechanism	Meroterpenoid with no clearly defined molecular target; limited bioactivity reported.
Primary Target	Not identified
Pathway	Meroterpenoid biosynthesis pathway
Chemical Class	Meroterpenoid (PKS釦erpene hybrid)
Discovery Year	2016
Keywords	meroterpenoid natural productpolyketide-terpenoid hybridtalaromyces metaboliteendophytic fungus metabolitequinone-related scaffoldsecondary metabolite research tool
References	Harned et al., Phytochemistry, 2016 (isolation and structure elucidation of talarolutins A縫; bioactivity evaluation) DOI: 10.1016/j.phytochem.2016.03.013
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