Enterocin – Ribosomally synthesized bacteriocin that f...

For Research Use Only. Not for human or veterinary use.

Enterocin Product ID: BLK-0950
Structure
CAS	59678-46-5
Molecular Formula	C22H20O10
Molecular Weight	444.39
Price	1mg: USD 150.00 / 5mg: - / 25mg: -
Storage	-20°C
Solubility	1mg/ml ethanol, methanol, DMSO
Purity	>95%
Source Organism	Streptomyces sp.
Summary	Enterocin Ribosomally synthesized antimicrobial peptide that disrupts Gram-positive bacterial membranes.
Details	Enterocin refers to a family of bacteriocins produced by Enterococcus species that inhibit closely related Gram-positive bacteria. These peptides act primarily by inserting into the bacterial membrane, forming pores that disrupt membrane integrity and lead to leakage of cellular contents, chromosomal condensation, and cell lysis. Immunity and cross-resistance mechanisms are mediated by dedicated ABC transporter systems that protect producer strains. Due to strong antimicrobial and biofilm-inhibitory properties, enterocins are widely investigated as natural food biopreservatives and as potential alternatives or adjuvants to antibiotics.
Mechanism	Ribosomally synthesized bacteriocin that forms membrane pores in Gram-positive bacteria, causing cytoplasmic leakage.
Primary Target	Bacterial cytoplasmic membrane
Pathway	Bacterial membrane integrity; ABC transporter-mediated immunity
Chemical Class	Ribosomally synthesized peptide (bacteriocin)
Discovery Year	1978
Keywords	bacteriocin peptidemembrane-permeabilizing agentgram-positive bacteria inhibitorpore-forming peptideenterococcus-derived peptideantimicrobial research tool
References	Klaenhammer et al., Arch Microbiol, 1978 DOI: 10.1007/BF02565084 Soni et al., Microorganisms, 2022 DOI: 10.3390/microorganisms10040684 Grande Burgos et al., Microorganisms, 2021 DOI: 10.3390/microorganisms9071411 Benmouna et al., Antibiotics, 2023 DOI: 10.3390/antibiotics12071188
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