For Research Use Only. Not for human or veterinary use.
Aspergillimide
Product ID: BLK-0321
Structure
CAS
195966-93-9
Molecular Formula
C20H29N3O3
Molecular Weight
359.47
Price
1mg: USD 100.00 / 5mg: - / 25mg: -
Storage
-20°C
Solubility
1mg/ml ethanol, methanol, DMSO
Purity
>95%
Source Organism
Aspergillus japonicus.
Summary
Aspergillimide Indole alkaloid from Aspergillus species with anthelmintic activity.
Details
Aspergillimide is a secondary metabolite produced by an Aspergillus species and belongs to a class of indole alkaloids structurally related to paraherquamides. It differs from paraherquamides by the loss of the dioxygenated seven-membered ring and the fused phenyl ring, instead possessing a C8-keto group. Aspergillimide exhibits anthelmintic activity and represents a structurally simplified scaffold within the paraherquamide family of nematocidal fungal metabolites.
Mechanism
Anthelmintic indole alkaloid; precise molecular target not fully established.
Primary Target
Not fully defined (nematode neuromuscular target inferred)
Pathway
Neuromuscular signaling pathway
Chemical Class
Indole alkaloid
Discovery Year
1997
Keywords
anthelmintic natural productindole alkaloidnematode inhibitorparaherquamide analogueaspergillus metabolitesecondary metaboliteantiparasitic research tool
References
Banks RM et al., J Antibiot (Tokyo), 1997, 50:840-846