Circumdatin F – Reported antiviral and antifouling alkaloi...

For Research Use Only. Not for human or veterinary use.

Circumdatin F Product ID: BLK-1520
Structure
CAS	232922-23-5
Molecular Formula	C17H13N3O2
Molecular Weight	291.13
Price	1mg: USD 360.00 / 5mg: - / 25mg: -
Storage	-20°C
Solubility	1mg/ml ethanol, methanol, DMSO
Purity	>95%
Source Organism	Aspergillus westerdijkiae.
Summary	Circumdatin F Fungal quinazolinobenzodiazepine alkaloid studied in antiviral research.
Details	Circumdatin F is a quinazolino[3,2-a][1,4]benzodiazepinedione alkaloid isolated from Aspergillus species. It has been reported to inhibit the final stage of hepatitis C virus polyprotein processing and exhibits activity in antifouling models by modulating marine microbial community composition. Structurally, it contains fused quinazolinone and benzodiazepinone moieties typical of fungal benzodiazepine alkaloids. Circumdatin F serves as a useful scaffold for studying antiviral mechanisms and environmentally friendly antifouling strategies.
Mechanism	Reported antiviral and antifouling alkaloid; precise molecular target not fully characterized.
Primary Target	Hepatitis C virus replication complex
Pathway	Viral replication pathway
Chemical Class	Quinazolinobenzodiazepine alkaloid
Discovery Year	2000
Keywords	quinazolinobenzodiazepine alkaloidantiviral compoundhcv polyprotein processing inhibitorantifouling agentmarine biofilm modulatoraspergillus metabolitebenzodiazepine scaffoldnatural product research tool
References	Arai et al., J Nat Prod, 2000 DOI: 10.1021/np000381u Takahashi et al., J Org Chem, 2001 DOI: 10.1021/jo001696h Chen et al., Sci Total Environ, 2021 DOI: 10.1016/j.scitotenv.2021.152910
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