For Research Use Only. Not for human or veterinary use.
Dihydrochlamydocin
Product ID: BLK-0820
Structure
CAS
157618-75-2
Molecular Formula
C28H40N4O6
Molecular Weight
528.65
Price
1mg: USD 190.00 / 5mg: - / 25mg: -
Storage
-20°C
Solubility
1mg/ml ethanol, methanol, DMSO
Purity
>95%
Source Organism
Verticillium sp.
Summary
Dihydrochlamydocin Cyclic tetrapeptide that inhibits histone deacetylases (HDACs).
Details
Dihydrochlamydocin is a cyclic tetrapeptide fungal metabolite structurally related to chlamydocin and HC-toxin. Conformational studies reveal a constrained bis-?-turn backbone that supports its bioactive configuration. It acts as a histone deacetylase (HDAC) inhibitor, modulating chromatin acetylation and affecting transcriptional regulation. Due to its epigenetic activity, dihydrochlamydocin is used as a chemical probe in studies of chromatin biology and cancer-related gene expression.
Mechanism
Histone deacetylase (HDAC) inhibitor that increases histone acetylation and alters gene expression.